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Fluctuating levels of cholesterol and triglycerides vs higher risk of developing dementias

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Fluctuating levels of cholesterol and triglycerides vs higher risk of developing dementias

Dr.P.Harinath by Dr.P.Harinath
July 16, 2023
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Fluctuating levels of cholesterol and triglycerides in their blood may have a higher risk of developing Alzheimer’s disease and related dementias

  • A new study suggests that older adults with fluctuating levels of cholesterol and triglycerides in their blood may have a higher risk of developing Alzheimer’s disease and related dementias compared to those with stable levels.
  • The research, published in the journal Neurology, examined data from nearly 12,000 adults aged 60 or older without a prior dementia diagnosis. Participants with the greatest variability in total cholesterol had a 19% higher risk of dementia, while those with the most variation in triglyceride levels had a 23% greater likelihood. However, fluctuations in HDL and LDL cholesterol did not show a significant link to dementia risk.
  • The study highlights the potential importance of identifying individuals at higher risk through routine screenings and understanding the mechanisms behind lipid level changes.
  • Further research is needed to confirm the findings and explore preventive strategies.
Source: Association Between Fluctuations in Blood Lipid Levels Over Time With Incident Alzheimer Disease and Alzheimer Disease Related Dementias | Neurology
Dr.P.Harinath

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