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Home Mnemonics

Immunology Mnemonics

Dr.NM Tamilmani by Dr.NM Tamilmani
August 30, 2021
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Immunology Mnemonics


C

Celiac sprue features: CELIAC:

  • Cell-mediated autoimmune disease
  • European descent
  • Lymphocytes in Lamina propria/ Lymphoma risk
  • Intolerance of gluten (wheat)
  • Atrophy of villi in small intestine/ Abnormal D-xylose test
  • Childhood presentation

Atrophied villi cause less absorption, so diarrhea, weight loss, less energy.

    • Author: Robert O’Connor University College Dublin

 

Complement cascade initiating items: alternative vs. classic

  • Classic: Combined C
  • Alternative: Activators Alone, or IgA.

Complexes are made of Ab and Ag combined together.

Examples of activators: endotoxin, microbial surface.

    • Author: Robert O’Connor University College Dublin

 

Complement: function of C3a versus C3b

  • C3a: Activates Acute [inflammation].
  • C3b: Bonds Bacteria [to macrophages–easier digestion].

If wish to know more than just C3:

  • C3a, C4a, C5a activate acute.
  • C3b, C4b bind bacteria.
    • Author: Robert O’Connor and Marcus Fidel University College Dublin and UNM

D

DiGeorge Syndrome: features

The disease of T’s:

  • Third and 4th pharyngeal pouch absent.
  • Twenty-Two chromosome
  • T-cells absent
  • Tetany: hypocalcemia
    • Reference: http://medicalmnemonics.com/

G

Graves disease: etiology

  • In Graves disease, the thyroid-stimulating immunoglobulins are of the IgG
    • Reference: http://medicalmnemonics.com/

 

Goodpasture’s Syndrome components

  • GoodPasture is Glomerulonephritis and P

From autoantibodies attacking Glomerular and Pulmonary basement membranes.

    • Author: Robert O’Connor University College Dublin

H

Hypersensitivity reactions: Gell and Goombs nomenclature: ACID:

From I to IV:

  • Anaphylactic type: type I
  • Cytotoxic type: type II
  • Immune complex disease: type III
  • Delayed hypersensitivity (cell mediated): type IV
    • Reference: http://medicalmnemonics.com/

 

Hypersensitivity: type IV example

  • Poison IVy causes type IV
    • Reference: http://medicalmnemonics.com/

I

Immunoglobulin (Ig) types: the important ones worth remembering, in order of appearanceMAGDElaine (a girl’s name):

  • IgM
  • IgA
  • IgG
  • IgD
  • IgE

Magdelaine tells you the order they usually appear: M first, then A or G.

Alternatively: IgM is IMmediate.

    • Author: Magdelaine Deeby and Anonymous Contributor University College Dublin and University of Aberdeen

 

Immunoglobulins, and order B cells present them: MADGE (character from the old dishwashing liquid commercial):

  • IgM
  • IgA
  • IgD
  • IgG
  • IgE

Order of presentation by B cells (which is made first, IgD or IgM?) B cells present IgM primarily, and then IgD.

Just remember why all of us are going through this pain…to become M.D’s. For a B cell to be competent, it must get its MD.

Finally, by the same rule, B cells must first release M then G immunoglobulin on primary exposure.

    • Author: Tevis Anthony Verrett Creighton University School of Medicine

 

Immunoglobulins: which crosses the placenta

  • IgG crosses the placenta during G
    • Reference: http://medicalmnemonics.com/

 

Interferon gamma: action on macrophages: “Th1nk BIG Mac Attack“:

  • Th1 and NK cells Build Interferon G

Causes Macrophages to have an augmented Attack [by better lysosome function and increasing reactive oxygen metabolites, nitric oxide and defensins].

    • Author: Lior Greenberg Technion Faculty of Medicine, Haifa, Israel

L

Lupus signs and symptoms: SOAP BRAIN:

  • Serositis [pleuritis, pericarditis]
  • Oral ulcers
  • Arthritis
  • Photosensitivity
  • Blood [all are low – anemia, leukopenia, thrombocytopenia]
  • Renal [protein]
  • ANA
  • Immunologic [DS DNA, etc.]
  • Neurologic [psych, seizures]
    • Author: Ken Evans Saskatchewan Health, Acute and Emergency Services

M

MHC I vs. MHC II properties:“Immunity helps to exterminate fun for bacteria”

    • Author: Robert O’Connor University College Dublin

S

Sjogren syndrome: morphology: “Jog through the MAPLES“:

Sjogren is:

  • Mouth dry
  • Arthritis
  • Parotid enlarged
  • Lymphoma
  • Eyes dry
  • Sicca (primary) or Secondary
    • Author: Author: Robert O’Connor University College Dublin

T

T and B cells: types: When bacteria enter body, T-cell says to B: “Help Me Catch Some!” B-cell replies: “My Pleasure!”:

­ T-cell types:

  • Helper
  • Memory
  • Cytotoxic
  • Suppressor
  • ­ B-cell types:
  • Memory cell
  • Plasma cell
    • Author: Harsh Sharma BJMC, Pune, India
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